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Showing posts with the label Histology

Hereditary Haemochromatosis (HFE): Causes, Symptoms, Diagnosis & Treatment

By Sam
Hereditary Haemochromatosis (HFE): Causes, Symptoms, Diagnosis, and Treatment Complete article to Iron Overload Disorder | Symptoms, Genetics, Testing, and Management Hereditary Haemochromatosis (HFE) is one of the most common genetic disorders affecting iron metabolism in the human body. Despite its prevalence, it remains widely underdiagnosed due to its slow progression and non-specific early symptoms. This condition leads to excessive absorption and accumulation of iron in vital organs such as the liver, heart, pancreas, joints, and skin. Over time, this excess iron can cause serious and potentially life-threatening complications. In this comprehensive article, we will explore what Hereditary Haemochromatosis is, how it develops, its genetic basis, symptoms, diagnostic methods, treatment options, lifestyle modifications, and long-term outlook. This article is designed to be informative, easy to understand, and valuable for patients, caregivers, medical students, and hea...
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How To Learn The Breast Cancer ? Diagnosis, Treatment

By Sam
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 Chapter Orientation The breast is a modified skin appendage which has functional and social significance in the females but is rudimentary in the males. Onset of its development in females is linked to menarche as a part of developmental milestones in puberty. The breast responds to hormonal changes in reproductive years of a woman's life-during pregnancy, lactation, and post-menopausal and age-related involution. Like in other organs, the breast too is affected by anomalies, inflammatory diseases, and is the site of occurrence of benign and malignant neoplasms. However, the most important purpose of study of diseases of the breast is early detection and diagnosis of breast cancer, a disease that leads other cancers in incidence and mortality in women. Topics for study of breast diseases are discussed in this chapter under following headings:  1) normal structure. 2) inflammatory conditions, 3) benign epithelial proliferations, 4) benign fibroepithelial tumours, and 5) carcin...
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Histology 2year Question

By Sam
 Very Short answer  What is tissue and classification of tissue What Is paraffin Define H&E staining Name special stain for connective tissue Principal of gram stain Name stain used in cytological study . What is metachromatic stain with example Define dark ground microscope Special stain for carbohydrates What is pigment in the tissue Shot questions Define metachromasia and discuss any one metachromasia dye Special stain for muscle fibres Special stain for elastic fibres What is minerals and pigment in the tissue and demonstration? Describe hematoxylin stain and it's importance in histology Essay types Questions Definition microscope and their maintenance magnification power all types of microscope and discuss working principle of dark ground microscope and interference microscope Describe epithelial tissue and classification functions of Epithelial Tissue and classification functions of connective tissue.
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Hematoxylin & Eosin Staining

By Sam
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 Dye chemistry and staining procedure Introduction The Hematoxylin and Eosin stain (H&E) is the most widely used histological stain because : comparative simplicity Ability to demonstrate clearly an enormous number of different tissue structures. Hematoxylin stains cell nuclei blue black  shows good intranuclear detail. Eosin stains cell cytoplasm and most connective tissue fibers in varying shades and intensities of pink, orange, and red. Basics of Staining Stains >chemical substances used to achieve visible color contrast in the microscopic picture of a prepared tissue Staining >treating tissues or cells with a series of reagents so that it acquires a color; no particles of dye are seen and the stained element is transparent Purpose of Staining Outlines tissues and cellular components. Identification of tissues. Establishes the presence or absence of disease processes. Common Staining Method  Most commonly used staining methods are – Hematoxylin and Eos...
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Tissue Processing tissue collection BMLT

By Sam
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Histopathology in Practice BMLT Sample Reception,  Sample records Labelling of histology Histology The science concerned with the microscopic structure of tissues and organs in relation to their function. Also called microanatomy Specimen Reception Specimen Unpacking Specimen QC Specimen Labelling Sample Documenting Cassetting Specimen Dissection the stage  Dissecting props Cutting board Forceps Ruler Scalpel / knives / saw Inks / dyes Cassettes / lids Biopsy pads / tissue Filter bags Weighing scales Cut-up dictation Morphology” computer system “Dragon” dictation system Hands-free Just scan the barcode and away we go!! Specimen Categories A. Specimens only requiring transfer from container to tissue cassette. B. Specimens requiring transfer but with standard sampling, counting, weighing or slicing. C. Simple dissection required with sampling needing a low level of diagnostic assessment and/or preparation. D . Dissection and sampling required needing a moderate leve...
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