Hereditary Haemochromatosis (HFE): Causes, Symptoms, Diagnosis & Treatment

Hereditary Haemochromatosis (HFE): Causes, Symptoms, Diagnosis, and Treatment Complete article to Iron Overload Disorder | Symptoms, Genetics, Testing, and Management Hereditary Haemochromatosis (HFE) is one of the most common genetic disorders affecting iron metabolism in the human body. Despite its prevalence, it remains widely underdiagnosed due to its slow progression and non-specific early symptoms. This condition leads to excessive absorption and accumulation of iron in vital organs such as the liver, heart, pancreas, joints, and skin. Over time, this excess iron can cause serious and potentially life-threatening complications. In this comprehensive article, we will explore what Hereditary Haemochromatosis is, how it develops, its genetic basis, symptoms, diagnostic methods, treatment options, lifestyle modifications, and long-term outlook. This article is designed to be informative, easy to understand, and valuable for patients, caregivers, medical students, and hea...

Red blood cell count

 Red blood count (RBC) is a blood test that tells you how many red blood cells you have.

RBC


Red blood cells contain a substance called hemoglobin, which carries oxygen throughout the body.

The amount of oxygen brought into your body's tissues depends on the number of red cells you have and how well they function.

RBC counts are usually performed as part of the total blood count (FBC).

Women tend to have lower RBCs than men, and red cell count tends to decrease with age.

A normal RBC count would be:

  • men – 4.7 to 6.1 million cells per microlitre (cells/mcL)
  • women – 4.2 to 5.4 million cells/mcL
The results of the RBC count can be used to diagnose blood-related conditions, such as iron deficiency anemia (when there are fewer red blood cells than normal).

Low RBC levels may also indicate a deficiency of vitamin B6, B12 or folate.

It can also indicate internal bleeding, kidney disease or malnutrition (when a person's diet does not have enough nutrients to meet his or her body's needs).

High RBC counts can be caused by a number of health conditions or health-related factors, including:

  • smoking
  • congenital heart disease
  • dehydration (for example, from severe diarrhea)
  • low oxygen levels in the blood (hypoxia)
  • pulmonary fibrosis (a condition of the lungs that causes lung shock)
Learn more about red cell counts in Lab Tests Online

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