Hereditary Haemochromatosis (HFE): Causes, Symptoms, Diagnosis & Treatment

By Sam
Hereditary Haemochromatosis (HFE): Causes, Symptoms, Diagnosis, and Treatment Complete article to Iron Overload Disorder | Symptoms, Genetics, Testing, and Management Hereditary Haemochromatosis (HFE) is one of the most common genetic disorders affecting iron metabolism in the human body. Despite its prevalence, it remains widely underdiagnosed due to its slow progression and non-specific early symptoms. This condition leads to excessive absorption and accumulation of iron in vital organs such as the liver, heart, pancreas, joints, and skin. Over time, this excess iron can cause serious and potentially life-threatening complications. In this comprehensive article, we will explore what Hereditary Haemochromatosis is, how it develops, its genetic basis, symptoms, diagnostic methods, treatment options, lifestyle modifications, and long-term outlook. This article is designed to be informative, easy to understand, and valuable for patients, caregivers, medical students, and hea...
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Entamoeba Gingivalia Epidemiology

By Sam

Entamoeba Gingivalia

  1. Only trophozoite stage of Entamoeba Gingivalia is obtained but no cyst occurs.
  2. The size of the trophozoite is 10 to 20 mm. Actively motile multiple pseudopodia along the epithelial cell with bacteria ingesting food vacuoles in the cytoplasm.
  3. Nucleus rounded shape central karyosome and nuclear membrane cause chromatin granules in line.
Entamoeba Gingivalia Trophozoite
Entamoeba Gingivalia Trophozoite

Mode of Transmission :-

By Direct Oral Contact And Droplets Of Saliva And Clomid.

Epidemiology:- 

It is obtained in vaginal and cervical smears when humans use intrauterine devices in a contaminant manner.It Appears in Dog, Cat and Monkey's Mouth.

Giardia lamblia

Geographical Distribution- World Wide

Habitat:- 

Present in the upper part of duodenum and jejunum. Most Common Intestine Protozoa Flagella Pathogen That Cause Diarrhoea.

Marphology :-

On the basis of morphology it is divided into two faces.
  1. Trophozoites 
  2. Cyst
1. Trophozoites :-
Rounded anterior and posterior or size 14πm Long, 9πm width and 4πm thick


  1. When viewed in fat lay form, it appears like tennis and badminton rackets and looks like a layer when viewed from the side.
  2. Its dorsal surface and ventral surface are tightened
  3. Its anterior end is broad and rounded and its posterior end is shaped like a point.
  4. Its body is bilaterally symmetrical and all the organs of the body are paralleled.
  5. Trophozoite is activaly motile.  The trophozoite longitundinal is divided by binary fission.With the help of sucking disc, villi and crypts found in the upper part of jejunum and duodenum are attached to the apical and feeding through pinotosis.

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